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M.K (Medications (Lorazepam 2mg/mL oral concentrate PRN q 4hrs (Adverse…

- - - - CNS: dizziness, drowsiness, lethargy, hangover, headache, ataxia, slurred speech, forgetfulness, confusion, mental depression, rhythmic myoclonic jerking in pre-term infants, paradoxical excitation
        EENT: blurred vision
        Resp: respiratory depression
        CV: rapid IV use only: APNEA, CARDIAC ARREST, bradycardia, hypotension
        GI: constipation, diarrhea, nausea, vomiting, weight gain (unusual)
        Derm: rashes
        Misc: physical dependence, psychological dependence, tolerance
  - - - CNS: NEUROLEPTIC MALIGNANT SYNDROME, extrapyramidal reactions, sedation, tardive dyskinesia
        EENT: blurred vision, dry eyes, lens opacities
        CV: ECG changes, hypotension, tachycardia
        GI: constipation, dry mouth, anorexia, drug-induced hepatitis, ileus
        GU: pink or reddish-brown discoloration of urine, urinary retention
        Derm: photosensitivity, pigment changes, rashes
        Endo: galactorrhea
        Hemat: AGRANULOCYTOSIS, leukopenia
        Metabolic: hyperthermia
  - - - CNS: confusion/excitement (especially in geriatric patients), dizziness, flushing, headache, insomnia, lightheadedness (IM, IV, subcut), nervousness
        EENT: blurred vision, cycloplegia, ↑ intraocular pressure, mydriasis, photophobia
        CV: palpitations, tachycardia
        GI: dry mouth, altered taste perception, bloated feeling, constipation, nausea, paralytic ileus, vomiting
        GU: erectile dysfunction, urinary hesitancy/retention
        Derm: ↓ sweating, urticaria
        Local: local irritation (IM, IV, subcut)
        Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS, fever (especially in children), suppression of lactation
  - - - CNS: agitation (↑ in children) (IV), anxiety (IV), headache (IV), fatigue (IV), insomnia (IV)
        Resp: atelectasis (↑ in children) (IV), dyspnea (IV)
        CV: hypertension (IV), hypotension (IV)
        GI: HEPATOTOXICITY (↑ DOSES), constipation (↑ in children) (IV), ↑ liver enzymes, nausea (IV), vomiting (IV)
        F and E: hypokalemia (IV)
        GU: renal failure (high doses/chronic use)
        Hemat: neutropenia, pancytopenia
        MS: muscle spasms (IV), trismus (IV)
        Derm: ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, rash, urticaria
  - - - GI: abdominal cramps, nausea, diarrhea, rectal burning
        F and E: hypokalemia (with chronic use)
        MS: muscle weakness (with chronic use)
        Misc: protein-losing enteropathy, tetany (with chronic use)
  - - - F and E: electrolyte imbalances, dehydration
        GI: abdominal cramps, nausea, vomiting, diarrhea
        Derm: rashes
        GU: urine discoloration
  - - - CNS: confusion, sedation, dizziness, dysphoria, euphoria, floating feeling, hallucinations, headache, unusual dreams
        EENT: blurred vision, diplopia, miosis
        Resp: RESPIRATORY DEPRESSION
        CV: hypotension, bradycardia
        GI: constipation, nausea, vomiting
        GU: urinary retention
        Derm: flushing, itching, sweating
        Misc: physical dependence, psychological dependence, tolerance
  - - - CNS: drowsiness, dizziness, headache, paradoxical excitation (increased in children)
        EENT: blurred vision, tinnitus
        CV: hypotension, palpitations
        GI: anorexia, dry mouth, constipation, nausea
        GU: dysuria, frequency, urinary retention
        Derm: photosensitivity
        Resp: chest tightness, thickened bronchial secretions, wheezing
        Local: pain at IM site
  - - - GI: diarrhea, nausea, stomach pain (large doses), vomiting
        Derm: contact dermatitis, Stevens-Johnson syndrome
- - - - Obstruction of the superior vena cava
      - Spinal cord compression
      - Bone metastasis
      - Joint effusions
      - Infection
    - - Fever
      - Night sweats
      - Weight loss
      - Pruritis
      - Malaise
    - - Anemia
        
        Manifestations
        
        Pallor
        
        Fatigue
        
        Malaise
        
        SOB
        
        Decreased activity tolerance
      - Thrombocytopenia
        
        Manifestations
        
        Petechiae
        
        Bleeding gums
        
        Easy bruising
        
        Occult hematuria
        
        Retinal hemorrhages
      - Leukopenia
        
        Manifestations
        
        Infection
      - Infiltration of neoplastic cells in bone marrow
        
        Bone pain
      - Mouth pain (stomatitis)
    - - Cancer originating from lymphatic cells such as B, T, and NK cells leading to the development of tumors within the lymphatic system