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Sleep and Memory (Slow Wave Sleep (preplay and replay in the hippocampus…
Sleep and Memory
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Long-term memory
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retained in anterograde amnesia, while
partially lost in retrograde amnesia.
Short-term memory
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consolidated through the formation of sleep
spindles and SWRs, indicative of preplay
and replay in the hippocampus
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retained in retrograde amnesia, while lost in anterograde amnesia
Learning
our ability to rapidly form new memories for episodes, but also to maintain stable representations over time is dependent on a balanced tradeoff between stability and plasticity
learning is associated with structural changes ─ sleep promotes the branch-specific formation of dendritic spines following learning.
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also associated with the consequent
removal of old dendritic spines to be
replaced by new dendritic spines.
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mechanism proceeds as:
① learning
② reactivation and consolidation during SWS
③ dendritic spine formation
④ formation of memory
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