Please enable JavaScript.
Coggle requires JavaScript to display documents.
Immune System Cells/Organs (Neutrophils (Attracted to foreign material…
Immune System Cells/Organs
Myeloid Cells
Myeloid Progenitor
Granulocytes
Platelets
Monocytes
Macrophges
Mast Cell
RBC's
Lymphoid Cells
Lymphoid Progenitor
Lymphocytes
Mononuclear Cells
T Cells
B Cells
NK Cells
Innate Cells
NK Cells
Granular Lymphocytes
cytotoxic (cell killing)
Do not clonanly expand
ALL Myeloid Cells
Adaptive Cells
T Cells
Mature in Thymus
B Cells
Mature in Bone Marrow
Primary and Secondary Lymphoid Organs= HOME
Naive T and B cells circulate between blood and secondary lymphoid
Primary
Remove self reactive clones
Bone Marrow + Thymus
Secondary
In contact with antigen presenting cells/ antigen
Spleen, lymph node, tonsils
Neutrophils
30 min to leave blood and activate in tissue
Attracted to foreign material
Inflammation
Bacteria
Attracted by chemotaxis
Lets other motile cells be attracted to high concentration of chemical
Engulfs bacteria, releases enzymes + hydrogen peroxide from granules and kills
Produced in= Bone Marrow
Most Common WBC
Serious Infection: PUS= dead neutrophils
Performed Granules
Rapidly released
Activates degranulation
Eosinophils & Basophils
Eosinophils
Target Parisites
Lungs
Skin
Basophils
Histamine
(+ Mast Cells)
Allergic Reactions
Monocytes
released by BONE MARROW
Float in bloodstream
Enter tissue + differentiate= MACROPHAGES
7% of leucocytes
MACROPHAGES
Most boundary tissues have macrophages (specific)
Brain: Microglia
Lung: Alveolar Macrophages
Clean up dead neutrophils in pus
DENDRITIC CELLS
1) Capture Pathogens
2) Break down pathogens into peptides to present
Adaptive Immune Response
3) Present on their surface in specialised presenting molecules = MHC
Professional Antigen Presenting Cells
4) migrate to lymph nodes
5) Present to T Cells