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Task 1
Evolution of aging (Food restriction (3 hypotheses (Life extension…
Task 1
Evolution of aging
Evolutionary perspective
Theories
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Pleiotrophy
Pleiotropic genes (multiple traits) with good early effects favored by selection, even if they have bad late effects
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General pattern of gene action #
Disposable soma theory
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studies support the idea that it is the evolved capacity of somatic cells to carry out effective maintenance and repair that governs time taken for damage to accumulate which regulates longevity
Shift of resources away from reproduction during famine, when reproductive success will be small, to increased somatic maintainence #
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Reproduction
Semelparity
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Chance of surviving second breed is 0 so after reproduction sudden collapse of maintenance and repair
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Explanation
All energy goes to reproductive success, after that no resources are left
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Food restriction
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Humans
longevity of institutionalized, mentally retarded, castrated men was greater than intact men (matched)
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Aging
Progressive loss of function accompanied by decreasing fertility and increasing mortality with advancing age
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