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Gene Regulation (Cell communication (Receptor Types (G-protein coupled,…

- - - - important in signaling and activation processes
- - - - molecule that deforms repressor from binding to operator
        
        lactose becomes allolactose
    - - Repressor
    - - CRP/cAMP holds RNA pol from falling off
        
        glucose inhibits cAMP
- - - - heterochromatin: silenced confirmation
      - euchromatin: open confirmation
      - methylation= repressive/active depending on overall net modifications
      - acetylation: DNA opens by adding neg charged acetyl groups to lycine in histone tails
      - controlled by:
        
        transcription repressors
        
        Recruit corepressors
        
        transcription activators
        
        Recruit co-activator
        
        Recruit RNAP to promoter
  - - - imprinting = turned off
- - - - mutations= proteins end up in cytosol (lack of regulation)
- - - - hydrolytic enzymes
        
        only function in low pH (fail safe mechanism)
        
        mannose 6-phosphate tagged to end up in lysosome