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Interstitial Pulmonary Fibrosis/Peripheral Vascular Disease (Medical…
Interstitial Pulmonary Fibrosis/Peripheral Vascular Disease
Pathophysiology (IPF)
Risk Factors
Environmental pollutants
Viral infections
Cigarette smoking
Genetics
GERD
Medication
Chemotherapy drugs
Antibiotics
Heart medications
Anti-inflammatory drugs
Radiation treatments
Sex
Age
Occupation
Inhalation of Grain Dust
Anti-body response to foreign body
Inflammation of alveoli
Increases in fluid, protein and cells
Accumulation within alveoli
Decreased Gas Exchange
Compromised Lung Function
Post inflammation fibrosis
.
Pathophysiology (PVD)
Risk Factors
Age
HTN
Smoking
Hyperlipidemia
Stress
Diabetes
Sedentary Lifestyle
Obesity
Genetics
Thickening and hardening of arterial walls
#
Prolliferation of the intima layer
Infiltration of LDLs into sub-endothelial layer
LDLs become oxidized
Macrophages consume LDLs and form foam cells
Foam cells stimulate collagen and attract t-cells and macrophages
Plaque forms, grows in size
Clot formation (Intermittent Claudication)
Medical Management (IPF)
Chest X-rays
Anti-nuclear antibodies or Rheumatoid Factor
C-Reactive Protein/Erythrocyte Sedimentation Rate
CBC
ABG
High Resolution CT
Transthoracic echocardiography
Procedures/Surgical Management
Bronchoscopy
Surgical Lung Biopsy
Lung Transplant
Vaccinations for influenza/PNA
Pharmacotherapy
Systemic Corticosteriods
Immunosupressants
Tyrosine kinase inhibitors
Antifibrotic agents
Physical Therapy
Medical Management (PVD)
Diagnostic Testing
Ankle Brachial Index
Diagnostic Radiology
Doppler
Angiogram
Anti-thrombotic therapy
Aspirin
GP IIb-IIIa inhibitor
ADP Inhibitors
Hyper-lipedmia Control
Lipitor
Mevacor
Zocor
Crestor
Surgical Management
Endarterectomy
Arterial bypass graft of lower extremity
Signs and Symptoms (IPF)
#
Weight loss
Low grade fevers
Fatigue
Arthralgias
Myalgias
Dyspnea
Dry, hacking couch
Shortness of Breath
Gradual Unexpected Weight Loss
Clubbing of DIPs of fingers and toes
Signs and Symptoms (PVD)
#
Numbness or Coldness of Extremity
Aching joints & muscles
Fatigue
Weakness and Atrophy
Hair Loss of Extremities
Poor Wound Healing