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VON WILLIBRAND DISEASE (3 TYPES (TYPE 1 (MOST COMMON AND OCCURS IN 80% OF…
VON WILLIBRAND DISEASE
3 TYPES
TYPE 1
MOST COMMON AND OCCURS IN 80% OF CASES
ILLISTRATES A
QUANTITATIVE
DEFECT OF THE VON WILLIBRAND FACTOR IN THE PLASMA.
TYPE 2
ILLISTRATES a
qualitative
defect in the plasma
TYPE 3
VWF antigen is
absent
in the blood
or has low activity of VWF and
factor 8
therapeautic management determined
by these
5 factors
urgency
location
of surgical procedure
type
of vw disease
severity
of the vw disease
nature
Treatments include
Desmopressin
optimizes
plasma levels of
endogenous
vWF
cryoprecipitate
fibrinogen
factors 8 and 13
vWF
if VWF is the cause of bleeding it should be treated empirically then diagnosed later
lust (n)
