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13 - response to infection (Phases (T cells and abs go into circulation…
13 - response to infection
Phases
cross membrane
macrophages consume
dendrites travel to lymph node, drain to ?thymus
T cells and abs go into circulation
If Viral: CD 8 kills infected cells
Recruited effectors (mediated by diferrential cytokines)
1: Intracellural pathogen (bact, virus)
IL-12
3: extracellular pathogen (bact)
IL-17
IL-22
Parasite (Group 2 ILCs)
IL-13
IL-4
Homing of t-cells to site
Expression of chemokine
?
3 categ of chemokines
homeostatic
inflammation
mixed
Neurophils activated
Macrophages act
Eosi, mast, basoph activ.