Please enable JavaScript.
Coggle requires JavaScript to display documents.
Alzheimer's Disease (Clinical Presentation (difficulty organizing your…
Alzheimer's Disease
Epidemiology
-
-
by the year 2050, AD could affect 13.8 million persons in the United States
-
-
-
-
-
Pathophysiology
affects the 3 processes that keep neurons healthy: communication, metabolism, and repair.
certain nerve cells in the brain stop working, lose connections with other nerve cells, and finally die
neuritic plaques develop in the hippocampus, a structure deep in the brain that helps to encode memories, and in other areas of the cerebral cortex that are involved in thinking and making decisions
-
destruction and death of these nerve cells causes the memory failure, personality changes, problems in carrying out daily activities, and other features of the disease
tau protein in neurons detaches and forms an insoluble filament called neurofibrillary tangle, contributing to neuronal death
-
loss of synapses, acetylcholine, and other neurotransmitters contributes to the decline in memory and loss of other cognitive functions associated with Alzheimer's disease
-
-
Treatment
secondary symptoms such as depression, agitation, aggression, hallucinations, delusion, and sleep disorders can be treated with psychotropic medications
-
-
-
-