Please enable JavaScript.
Coggle requires JavaScript to display documents.
Acute Lymphocytic Leukemia (lab findings (CBC (low RBC (Litzow, 2014), low…
Acute Lymphocytic Leukemia
lab findings
blood clotting function
CT of lymph nodes
enlarged lymph nodes/spleen (Litzow, 2014).
spinal fluid analysis
bone marrow aspiration
20% of cells in bone marrow are lymphoblasts- definitive diagnostic test for ALL (Seiter, 2017).
stain slides with myeloperoxidase (MPO) and terminal deoxynucleotidyl transferase (TdT) to determine if leukemia is myeloid or lymphoblastic. If it is lymphoblastic, then the TdT stain will be positive (Seiter, 2017).
CBC
low RBC (Litzow, 2014)
low normal WBC (Litzow, 2014)
low platelet levels (Litzow, 2014)
low hemoglobin level (Litzow, 2014).
physical findings
anemic (Litzow, 2014)
shortness of breath (Litzow, 2014)
prone to bleeding (Litzow, 2014)
infection prone (Litzow, 2014)
enlarged spleen/lymph node due to lack of normal lymphocytes (Litzow, 2014).
cellular changes: immature lymphoblasts
(Litzow, 2014)
immature B lymphoblast
immature T lymphoblast
pathophysiology/etiology
immature, malignant B and T lymphoblasts form
(Litzow, 2014).
immature lymphoblasts crowd bone marrow (Litzow, 2014)
normal cells don't have space, can't form in bone marrow
(Litzow, 2014)
decreased cell numbers of RBC, WBC, platelets (Litzow, 2014).