Benign or malignant, Primary (rarely metastasize outside the CNS) or secondary (usually metastasized from lungs), Intracerebral or extracerebral Manifestations change in cognition or consciousness, headache DIagnostic exam of fundus of eye, visual fields, neurologic assessment, EEG, MRI, anteriograms, endocrine studies Collaborative Care Chemotherapy (overcome blood-brain barrier with implanted Ommaya reservoir, Convection-enhanced delivery, Biodegradable anhydrous wafers) Surgery (Burr hole, Craniotomy, Craniectomy, Cranioplasty) Radiation therapy (of choice for inaccessible tumors)