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Dysplasia (PMODs (Types of PMODs (Leukoplakia a white lesion, unable to…

- - - - INFO
        
        Information about the pt (age, gender, medical history, pt name)
        
        Clinical history of the lesion (onset, duration, pain, site, size, texture, overlying skin, fixation/mobility, one or more, pigmentation, previous surgery)
        
        Description of the lesion – similar to above, may help to accompany with photograph
        
        Results of investigations – hematological, microbiological, regional LN palpation, medical imaging
        
        Surgical history – resistance to knife cutting, presence of a capsule, amount of bleeding, exudates or fluids on incision
      - Biopsy Types
        
        Incisonal(sampled area)
        
        Excisional (whole area)
        
        Brush (collection smear)
        
        Aspiration (fluid removal)
      - INDICATIONS
        
        Obtain a definitive diagnosis
        
        To confirm and clinical diagnosis
        
        To eliminate other possible diagnoses
        
        To help plan definitive tx, clinical course and prognosis of a pt
        
        To reassure the anxious pt
        
        Medico-legal documentation
        
        Follow up or review surveillance
- - - - Squamous Cell Papilloma
        
        HPV-induced proliferation of stratified squamous epithelium
        
        Koilocytes in prickle cell layer
        
        Soft, painless, pedunculated, exophytic nodules = "cauliflower"
      - Verruca Vulgaris
        
        HPV-induced proliferation of stratified squamous epithelium
        
        usually found on the vermillion border/labial m./anterior tongue
        
        white, exophytic lesion
        
        elongated rete ridges, finger-like projections w/ chronic infiltrate
  - - - Lip OSSC
        
        Vermillion border area - associated areas of UV exposure
        
        Crusting, indurated, ulceration w/ bleeding, metastasis rare (2%)
      - Tongue OSSC
        
        50% of OSSC - posterior lateral & ventral surfaces
        
        Indurated hard mass, ulcerated
        
        metastasis early and common
        
        Architecture: Small small non-cohesive or large cohesive islands invasion into connective tissue
      - FOM OSSC
        
        35% of OSCCs
        
        usually following sublingual keratosis
        
        exophytic mass w/ ulceration
        
        metastasis common
      - Buccal/Palatal OSSC
        
        usually posterior mucosal regions
        
        painless, large exophytic mass
        
        assoc. w/ dysphagia and trismus
      - Clinical Features:
        Exophytic Growth - outward growth, indurated hard mass, irregular papillary surface, fixed, ulcerated, painless
        Endophytic Growth - depressed, rolled border, ulcerated, painless
        Bony Invasion - moth-eaten appearance w/ ill-defined margin