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NEUROPATHOLOGY CLASSIFICATIONS (Peripheral Nervous System (Infectious…
NEUROPATHOLOGY CLASSIFICATIONS
INFLAMMATION
Cause
Usually infection
Fungi
Protozoa
Viruses
Bacteria
Routes
Heamatogenous
Direct implantation
Trauma, Iatrogenic
Peripheral nerves
Local extension
Paranasal sinuses, Middle ear, Nasal cavity
Exudates
Fibrinous
Bacteria
Suppurative
Bacteria
Lymphoplasmocytic
Virus
Neurotropic
Rabies
Visna
Endetheliotropic
Pantropic
Canine Distemper
Infectious Bovine Rhinotracheitis
Granulomatous
Bacteria and fungi
Haemorrhagic
Septicaemia or infarcts
TRAUMA
Concussion
recovery
repeated/severe
Neuronal loss + haemorrhage
Death
Contusion
focal haemorrhage
Haemorrhage
Epidural, subdural, leptomeninges, cerebral
Laceration
Tearing of CNS
Bone fracture
Penetrating objects
most severe
risk of infection
Spinal cord
Concussion
#
Contusion
#
Haemorrhage
#
Compression
Within/ Outside spinal cord
Causes
Abscess
Fracture
Neoplasia
Intervertebral disk disease
Malformations
Wobbler Horses
stenotic myelopathy
malarticulation & malformation
C3-C4
Cervical malformation-malarticulation in dogs
Atlantoaxial subluxation of toy dogs
Gross
Indented/ flattened
Microscopic
Wallerian degenration
May progress to neuronal loss and malacia
Peripheral Nervous System
Trauma
Predisposed nerves
Superficial
Proximity to bone
Proximity to injection sites
Dystocia
Infectious
Neospora caninum
Equine guttaral pouch mycosis
Macaw wasting disease
Non-suppurative inflammation
GI dysfunction
Neuropathies
Breed-related
Degenerative
Equine laryngeal hemiplegia
left recurrent laryngeal n.
atrophy
left dorsal cricoarytenoid m.
inability to abduct arytenoid cartilage and vocal fold
partial occlusion
Toxic
Lead
Damage Schwann cells
demyelination
Nutritional
Vit A, Vit B
Copper deficiency
Swayback
associated with diabetes mellitus and hypothyroidism
Neoplastic