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NEPHROTIC PEDIATRIC KDIGO (relapse? (replase (protein-niệu > 3+, 3 ngày…
NEPHROTIC PEDIATRIC KDIGO
definition
Nephrotic syndrome
U Pr/Cr
>=2.0, > 300mg/dl +3 dipstick
hypercholesterolemia
(>250 mg/dL);
proteinuria >2g/m2/24h or >50mg/kg/24h
phù
hypoproteinemia
(serum albumin <2.5 g/dL)
Complete
remission
protein niệu <+1 dipstick
3 ngày liên tiếp
U Pr/Cr
<0.2
Partial remission
U Pr/Cr
0.2-2
protein niệu giảm >50%
No remission
U Pr/Cr> 2
protein niệu không tới 50%
Respone? (corticoid)
Initial responde
complete remission 4 ws
Initial
nonresponder
/
steroid resistance
NO
complete remission after 8 ws
relapse?
Frequent
relapse
=2/6ms after initial respone
=4/12ms
Infrequent
relapse
1/6ms after initial respone
1-3/12ms
replase
protein-niệu > 3+
3 ngày liên tiếp
U Pr/Cr> 2
Steroid
dependence (2x replase)
corticoid treatment time
14 ds
Late
nonresponder
Persistent proteinuria during 4 or more weeks of
corticosteroids following one or more remissions