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Lecture 17 (Non-competitive Inhibition (Either pure or mixed (Pure…

- - - - binding of the inhibitor has no influence over substrate-binding.
    - - binding of the inhibitor influences the substrate-binding mechanism.
  - - - decreases Vₘₐₓ ─ allosteric binding of the inhibitor destabilises conformation, conditions are no longer optimal as a result.
      - Kₘ stays the same ─ since the inhibitor has no influence in the binding mechanism of substrate.
    - - decreases Vₘₐₓ due to the same reasons as in pure NC inhibition.
      - increases Kₘ ─ because substrate-binding is influenced, more is needed for effective tries.