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Haemoglobin
Stabilisation (Structural
Stabilisation (determined by
two…
Haemoglobin
Stabilisation
T-state
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allosterically stabilised by 2,3-bisphosphoglycerate
binds to the middle of the Hb molecule, essentially "jamming" the molecule in the T-state.
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Concerted
Model
a model of Hb-substrate interaction that shows an equilibrium reaction between the Hb R-state and T-state.
Sequential
Model
a model of Hb-substrate interaction that shows a progressive relationship from the R-state to T-state.
Structural
Stabilisation
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the haem group binds to histidine residue on the haemoglobin F-subunit, specifically the His8 residue.
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