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Brain development = Behavioral development (Proness to psychopathology:…

- - - - Primary sensorimotor cortices along with frontal and occipital pole matures first. The cortex develops in a parietal-to-front (back-to-front) direction. The superior temporal cortex, which contains association areas that integrate information from several sensory modalities, mature last.
      - temporal lobe followed a distinct patter maturation
        
        temporal pole matured early
        
        Most of the remaining temporal lobe matured during the age range for this samples except for a small are in the posterior part of the SuperiorTemporal Gyrus, which appeared to mature last -primary auditory cortex and language processing: Wernicke´s area.
      - Phylogenetically: latest developing areas are more evolved: prefrontal regions involved in executive control, decision-making and inhibition
      - the exact process underlying the GM loss is unknown:
        
        Cerebral white matter increases in the first four decades because of axonal myelination and may partially explain the observed GM loss
        
        Driven at least partially by synaptic pruning and trophic glial and vascular change and cell shrinkage