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Lymphatic/immune system (adaptive defenses of the T-lymphocytes (T cells…

- - - - triggering inflammation, chemotaxis for macrophages, compliment protein
- - - - localized, non-specific reaction to protect and begin repair of tissue
      - Basophils and mast cells (secrete heparin and histamine), neutrophils (phagocytic and cytotoxic), monocytes become macrophages (larger phagocytic cells than neutrophils)
      - phagocytic and cytotoxic, secrete H202 and hypochlorite, kill any living tissue around them as well as themselves (why this needs to be a localized response)
      - Chemical Mediators---interferons, pyrogens, the complement system
      - Histamine - from mast cells, basophils and platelets *MOST IMPORTANT VASODILATOR
        
        Kinins - polypeptides formed in the blood (Bradykinin is an example)
        
        Prostaglandins - from damaged cells, intensify 1 and 2
        Also, leukotrienes and complement
      - redness
        
        swelling
        
        heat
        
        pain
      - limit spread of pathogens
        
        remove debris from damaged tissue
        
        initiate tissue repair
- - - - a large phagocytic cell found in stationary form in the tissues or as a mobile white blood cell, especially at sites of infection.
  - - - promote inflammation when activated by innate or adaptive system.
  - - - recognize whole classes of cells, not specific kind of cell