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Task 9: Schizophrenia (Prognosis and predictors of functionality in…

- - - - This discovery of the grey matter (lateral ventrical prefrontal cortex) decrease before the onset led to probability to find a neurobiological marker for detecting people developing schizophrenia as well as preventative methods => Multi-modal strategies. For now, we should use a hybrid concept / window of opportunity (adolescents and young adults): symptom relief (symptom-based therapies) coupled to reduction of transition (course-alteration/disease modification).
    - - For those individuals who already have schizophrenia cannabis use can exacerbate symptoms (make the symptoms worse / more severe).
      - ‘A statistical association between cannabis consumption and schizophrenia does not necessarily imply a causal association. Cannabis consumption might, on the contrary, be caused by an emerging schizophrenia’.
      - Both Andréasson and Hall drew our attention to the importance of the stress-vulnerability model, which emphasizes the interplay between genes, environment and stress vulnerability in motivating people to use cannabis which may as a result trigger the disease
      - Dose–response relationship between cannabis use and schizophrenia
      - Cannabis to produce psychosis = no evidence