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The kidney's role in homeostasis (Regulate endocrine system and…
The kidney's role in homeostasis
3.Balance PH
Reabsorption of hydrogen and bicarbonate ions when needed
Excretion of excess hydrogen ions in urine e.g. during metabolic acidosis
Excretion of excess bicarb and hydrogen ions in urine
Reduce amount of hydrogen ions secretion during metabolic alkalosis
Regulate endocrine system and other hormones
Prostaglandin (vasodilator)
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Aldosterone (sodium reabsorbed)
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ANP (promote natriuresis and diuresis )
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Parathyroid hormone (Vitamin D)
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Antidiuretic hormone (water reabsorption)
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Renin (vasoconstrictor)
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Erythropoietin (RBCs)
1.Auto regulation of renal blood flow
Vasodilation of afferent arteriole
Vasoconstriction of efferent arteriole
Filters and eliminate metabolic waste and other toxins.
BUN
Creatinine
urea
drugs
Regulate glucose eg. insulin metabolism
Plasma osmolality
triggered high osmolality and reduce B/P
Regulate Blood Pressure
cardiac output
peripheral vascular resistance
Maintains electrolytes concentration eg. Na+, Mag, Cl, K+, PO4, Ca etc
reabsorption when needed
secretion of excess and eliminate in urine
adequate blood flow result in adequate renal perfusion
maintained constant hydrostatic pressure
regulate Ca, PO4