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enzyme (inhibitor (competitive (active site(noncovalent), Km↗),…
enzyme
inhibitor
competitive
active site(noncovalent)
Km↗
noncompetitive
↙Vm
allosteric site(noncovalent)
irreversible
active site(covalent)
prevent it from chemical reaction
additional factor
bind
cofactors(ions)
coenzymes(organic)
attach
prosthetic groups(permanently)
environment
ph：decreased,cytosolic
ionic condition
T：unfold,lose shape→inhibit
ribozymes
processing of RNA
spliceosomal RNA
remove intron
RNase P
cleave ptRNA
synthesis of polypeptides
(ribosome)
catalyzes covalent bond