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skeletal muscle filaments (thin filaments (troponin (the lock, a globular…
skeletal muscle filaments
thick filaments
myosin
one pair of heavy chains
(form the tail)
two pairs of light chains
(form two myosin heads)
the two light chains form the two myosin heads: this is where actin binds and where ATP will bind and be hydrolyzed
thin filaments
F-actin
filamentous actin
is two twisted rows of globular G-actin
the active sites on G-actin bind to myosin
nebulin
holds F-actin strands together
tropomyosin
is a double strand
prevents actin-myosin interaction by covering G-actin binding sites
troponin
the lock
a globular protein
binds tropomyosin to G-actin
has a receptor for
Ca2+ (the key
)
titin holds myosin bundle to the z-line