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OCD (Theories (Dual-systems (Results (weaker outcome devaluation…

- - - - Serotonine disruption
        
        also other disorders
        
        Hypersensitivity of postsynaptic receptors
      - Abnormal dopamine system
        
        inconsistant results
    - - Frontal orbito-striatal area
        Dorsolateral pfc
        
        Inhibition of response, planning, organisation and verification of previous action
        
        White matter anormalities in frontal reagions
      - Figure 1
    - - inflammation to basal ganglia
  - - - appraised as important
        
        suppresion or removal of intrusion
        Attempt to prevent harmful events
        
        Compulsions
        
        Distress reduction
        
        reinforcement
  - - - intrusive thought can make event happen
        
        probability TAF
      - morally equivalent
    - - depends on significance of thought
  - - - More important
    - - 4 actions x 5 times
        
        Candle
        
        turn it off/on and put it in a box
        
        Own compulsions
        
        2 neutral actions
      - Participants
        
        OCD
        
        Psychiatric controls
        
        Healthy controls
  - - - deficit in goal-directed action control, overreliance on habit
        
        impairement of frontostriatal loop
        
        OFC cingulate cortex, caudate nucleus
    - - goal directed
        
        can become habit
        
        slip of action
      - habit
    - - training stage
        
        learning stimuli-outcome
        
        Standard
        
        congruent
        
        incongruent
        
        baseline
      - tested goal directed vs habitual control
        
        questionnaire about the relationships
        
        outcome devaluation test
        
        goal directed learning
        
        slips of action test
        
        goal directed compete with habitual
        
        go no go
    - - feedback outcome unaffected
      - weaker outcome devaluation
        
        disturbance in goal-directed control
      - lack of sensitivity to devaluation
      - symptom severity predictive of performance on slips of action test
- - - - Repetitive behavior/mental acts in response to obsession or rules
      - Preventing/reducing distress or event
    - - most common
  - - - seperate in DSM5
- - - - 7 domains
        
        Physical health
        Emotional well-being
        Household duties
        Leisure
        Social relations
        Work
        School
      - Specific subtypes related to specific domains
        
        Hoarding
        
        Houshold
        
        Contamination
        
        Social relationships
        
        Sexual functioning
        
        Shame
        
        Heath
        
        Leisure
        
        Symmetry
        
        Social relationships
        
        Overresponsibility
        
        Health
        
        Taboo
        
        No specific subtype of QoL
      - scales
        
        Yale brown OC scale
        
        QoL
        
        Depression
- - - - More than 1h a day or Interfere with functioning
      - Distressing
      - Recognition of unreasonability (not in children)