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Introduction (Biomedical Applications (Organ System (uploaded image…
Introduction
Biomedical Applications
Skeletal System
Applications
Materials
Cardiovascular System
Applications
Silicone Rubber
Organ System
Silicone Rubber
Polyurethane
Poly-ACN
Tissue Replacement
Transplants
Definition
Types
Autograft
Harvest Donor Site => Transplant Host Site
Same Human Body
Allograft/Homograft
Same Species
Xenograft/Heterograft
Different Species
Graft = Transplant
Implants
Definition
Man-Made Materials => Host Living Tissues
Application Field
TE
Cell ECM Matrix: In Vitro => In Vivo
Engineered Tissues
Tissue Regeneration
Restore
Structure
Function
Behaviour
Performance
Comparison
Implants
Pros (RAA)
Reproducability
Reliability
Availability
Cons
Wear Debris
Interfacial Instability with Host Tissue
Biomech mismatch of elastic moduli
Transplants
Pros
Save lives
Cons
Surgery
Immunorejection
Infection
Organ Shortages
Materials
Biological/Natural
Definiton
Produced by biological system
Types
Characterisitics
Most Composites
In bodily fluids
Biomaterials
Applications
Biomaterials 1
Implant
Biomaterials 2
Biomedical Device
Types
Bioceramics
Cons
Brittle
Low Mechanical Relability
Machinability
Types
Bioglass
Alumina
Hydroxyapatitte
Pros
Good Biocompatibility
Corrosion Resistant
High Compression
Biometal/Bioalloys
Pros
Strength
Ductility
Machinability
Types
Ti Alloys
Gold
Stainless Steel
Cons
Compatibility
Corrosion
Allergic Reactions
Biopolymers
Pros
Versatility
Complex Shapes & Structures
Types
PS
PLA
PE
PGA
PEEK
Cons
Absorb fluid => Swellability
Poor mechanical strength
Leach undesirable products
Biocomposites/coatings
Dental Composite Resin
PE/HA Composite
Comparison
Difference
Viability
Ability to grow, live, develop
