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Deep Vein Thrombosis (Epidemiology (1 person in 20 will develop a DVT in…
Deep Vein Thrombosis
Treatment
Prophylactic anticoagulation (heparin, Lovenox, Xareto, etc.)
Thrombolytic therapy (Streptase, Activase, etc.)
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Pathophysiology
Inflammation leads to platelet aggregation and increased rate of fibrin formation causing increased rate of thrombus formation
Thrombus formation impairs valvular competence and increases vein wall fibrosis and increased blood reflux (CVI)
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Dependent on the Triad of Virchow: venous stasis, blood hypercoagulability, vein wall endothelial damage)
Epidemiology
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Approx. 80 cases per 100,000 Americans annually
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