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0927 Histology-Integumentary System (skin（organ） (two layer…

- - - - Papillary layer
        
        dermal papillae
        
        subpapillary plexus
        
        Meissner’s corpuscles (touch) & free nerve endings (pain and temp)
      - Reticular layer
        
        cutaneous plexus
        
        Tension lines of skin
    - - Cell types in the epidermis
        
        keratinocyte（90%）
        
        Differentiation
        
        Lamellar bodies
        
        Keratohyalin granules
        
        Melanocytes (8%) in stratum basale
        
        Langerhans cells in stratum spinosum
        
        Birbeck granules
        
        Merkel cells in basal layer
        
        Merkel’s corpuscle
      - 5 layers
        
        Stratum spinosum:
        
        Stratum granulosum
        
        Stratum lucidum
        
        refractile layer
        
        eleidin
        
        Stratum corneum:
        
        keratin filaments (soft keratin)
        
        Stratum basale
        (germinativum)
        
        stem cells
    - - superficial fascia
  - - - same number of cells,different amounts of pigment
    - - Cyanotic 發疳
        
        hemoglobin--purple-blue
      - Erythema 紅斑
        
        capillaries
      - Jaundice 黃疸
        
        liver disease--yellow bilirubin
  - - - Meissner's corpuscle
      - Merkel's corpuscle
      - Free nerve ending
      - Krause's end bulb
      - Ruffini's corpuscle
      - Pacinian corpuscle
    - - noradrenergic fibers
        
        Apocrine sweat glands
      - cholinergic fiber
        
        Merocrine (eccrine) sweat glands
- - - - isthmus
      - inferior segment
      - infundibulum
  - - - Holocrine glands
        
        in the dermis
        
        sebum-->acne
      - Duct
        
        open onto hair shafts
        
        from external root sheath
    - - Merocrine (eccrine) sweat glands
        
        Excretory duct
        
        Secretory portion
      - Apocrine sweat glands