Please enable JavaScript.
Coggle requires JavaScript to display documents.
Drug interactions (Risks for drug interactions (Drugs with high…
Drug interactions
Risks for drug interactions
Drugs with high bioavailability
Drugs that are bound to plasma proteins
Children
Drugs with small margins of safety
ELderly
Admin to medically comromised
Chronic use of druvs with long acting doses, excreted slwoly
Agonist reactions
CNS Depressant
CNS DEPRESSANT
Resp failure
=Enhanced depression,
Anticholinergic
+Anticholinergic, or antihist, or TCA
enhanced anticholinergic effect
Hypoglycemics
+salicylates
enhanced hypo
Neuromuscular blocker
+Antiarrhythmic,
neomycin
Enhanced neuromuscular
blockade
Calcium channel blocker
beta blocker
myocardialfailure
Beta blocker can mask effects of hypoglycemia
ACE inhibitor
increases insulin secretion
causes hypoglycemia
SSRI's
+tramadol
=seretonin syndrome
agitation
restlessness
shivering
atients taking ssri's avoid giving tramadol
oxycodone
codeine