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Emotion (Amygdala (Damage (Lateral Nucleus (Formation of type of…

- - - - Formation of type of association that elicits response
    - - Initiation of response (post processing)
  - - - Quick Thalamus --> Crude Signal to amygdala
    - - Slow processing confirming initial low road information
  - - - Modulates storage of emotional events
      - Indirectly strengthens memories of emotional events Easier to recall emotional/arousing information
      - Modulates arousal therefore modulating memory enhancement
      - FMRI: bidirectional modulation between A and cortical; increasing amount of stimuli that are linked to valiance stimuli
    - - Greater response for fearful faces
      - Greater response to subliminal stimuli
    - - Role in learning is expressed via our behavioural and physiological responses
      - Patients can report parameters of fear conditioning, just do not demonstrated the indirect fear response
- - - - Differences aren't due to task difficulty; Demonstrates multimodal effect; Impaired ToM, moral judgement & interpretation; Worse at emotional recognition than AD & Huntington; Impaired negative emotions; Impaired negative emotions
    - - Poor facial & dynamic emotional recognition
        
        Unable to recognise negative faces, and correlation between amygdala damage and their task performance Compared AD - sarcasm detection had greatest grey matter volume reduction in amygdala - but not unique to amygdala
        
        SPECT hypofusion correlates w/ behavioural symptoms
    - - Basic aversive stimuli - impairment in physiological response Variable results for complex stimuli i.e. startle reflex
    - - lower insight than other dementias
      - Correlation b/w quality of insight & grey matter in OFC & Frontopolar regions
      - Quality of emotional insight correlated to grey matter
    - - Grey matter volume associated w/ recognition of negative emotional faces