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Spiral Bacteria! (Mycobacteria (Mycobacterium Tuberculosis (Pulmonary…

- - - - Causes tuberculosis
      - M. Kansasii
      - M. Xenopi
      - M. Malmoense
  - - - Tuberculoid Leprosy (less serious)
        
        Thickening of peripheral nerves
        
        Hypopigemented skin lesions
        
        Th1 response predominant
      - Lepromatous Leprosy
        
        Intense edema
        
        Facial Lip Swelling
        
        Undifferentiated macrophages packed with AFB (Acid-Fast Bacilli)
        
        Th2 response predominant
      - Borderline Leprosy
        
        Balanced Th1 and Th2 response
        
        No giant cells
        
        Lymphocytic infiltrate and epitheloid cells
      - TREATMENT: Rifampicin (monthly, supervised) + Dapsone (daily, unsupervised) for 6 months
- - - - Blindness in neonate
      - Neonatal rash
      - Hutchinson's Triad in newborn: CN 8 deafness, Interstitial Keratitis, Hutchinson's teeth