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Anemia (↓ Production (Hormones (↓EPO -eg. chronic renal failure,…

- - - - Drugs
        -eg. PPIs, metformin
      - Vegan Diet
      - Pernicious anemia
    - - Malabsorption
      - Blood loss
      - Diet
  - - - Drugs
      - Irradiation
    - - Aplastic Anemia
      - Pure RBC aplasia
- - - - Metabolism defect
        
        G6PD deficiency
        
        Pyruvate Kinase deficiency
      - Hemoglobin defect
        
        Thalassemia
        
        Sickle cell disease
      - Membrane defect
        
        Spherocytosis
        
        Eliptocytosis
    - - Immune
        
        Autoimmune
        -eg. AIHA, SLE, RA, Hodgkin's lymphoma, CLL
        
        Alloimmune
        -eg. transfusion reaction, haemolytic disease of the newborn, transplant rejection
        
        Complement-mediated (rare)
        -eg. Paroxysmal nocturnal hemoglobinuria (PNH)
      - Non-immune
        
        DIC
        -Microangiopathic Haemolytic anemia
        
        Prosthetic valves
        
        Malaria
        -Plasmodium falciparum