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hormones that target the kidney (ADH (ADH2O) (origin: hypothalamus (there…
hormones that target the kidney
ADH
(ADH2O)
origin:
hypothalamus (there are osmolarity sensors there)
target:
collecting tubules
trigger:
elevated blood osmolarity (blood is not dilute enough)
result:
water is reabsorbed (increased blood volume)
a.k.a
vasopressin
aldosterone
origin:
adrenal cortex
target:
DCT
and
collecting tubules
trigger:
decreased Na+, increased K+, and H+
result:
increased water and Na+ re-absorption (increased blood volume)
ANP
origin:
right atrium of heart
target:
afferent arterioles
trigger:
increased blood volume
result:
increased filtration (less blood volume)
PTH
origin:
parathyroid gland
target:
DCT
trigger:
decreased CA++ in the blood
result:
increased Ca++ absorption
angiotensin II
origin:
liver
target:
afferent/efferent arterioles
trigger:
decreased BP
result:
at low doses causes preferential constriction of efferent arterioles (causes constriction of both @ high doses) which causes more pressure in the glomerulus (
raises CHP
) while
reducing renal blood flow
(so
GFR is maintained
)