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Numbness: A sensory abnormality that is negative VS. positive (parasthesia…

- - - - Consider distributions of peripheral nerve and look for motor signs => Nerve entrapment
        
        Ulnar nerve => cubital tunnel syndrome
        
        Peroneal or sciatic neuropathy
        
        Median nerve => Carpal tunnel syndrome
      - Dermatomal distribution of numbness and radicular pain/sciatica (radicular pain is directed along the course of the spinal nerve) => Radiculopathy. Can be in the cervical or lumbar regions.
      - Plexus injuries, e.g. Erbs; Klumpke
        
        Erbs (C5, C6) is an upper lesion. Note: loss of shoulder movement and elbow flexion (hand is held in waiter's tip position) + sensory loss over the lateral aspect of the arm and forearm
        
        Klumpke (C8, T1) is a lower lesion. Note: true claw hand with paralysis of all the intrinsic muscles; sensory loss along the ulnar side of the hand and forearm; Horner's syndrome
    - - Asymmetrical sensory and motor neuropathy involving separate seemingly random nerves => Mononeuritis multiplex. Associated with diabetes; autoimmune conditions (lupus, RA, vasculitis); paraneoplastic syndromes
      - Asymmetric and non length dependent sensory loss with sparing of motor function; possible ataxia and areflexia => Sensory neuropathy (rare), can be primary (DRG degeneration) or 2/2 platinum chemotherapy
  - - - Sensory cortex stroke BUT uncommon to have isolated sensory loss
      - Lacunar infarct
      - Spinothalamic sensory loss on ipsilateral face and c/l limbs => Lateral medullary syndrome. Look for other features of lateral medullary syndrome.