digestion of metabolites in the intestines
digestion of carbohydrates
digestion of proteins
micro-anatomy
villi
finger-like projections into the lumen which are covered in enteroctyes (which have microvilli on their apical surface)
contain a network of capillaries (all other nutrients go here) and a lacteal (dietary fat goes here)
intestinal crypts (mucosal glands)
rich in lymphocytes, eosinophils, and plasma cells
they also contain a few goblet cells
bordered on the bottom by the muscularis mucosae
digestion of lipids
only monosaccharides can be absorbed by enterocytes
pepsinogen (from chief cells) is activated to pepsin which cuts up proteins into amino acids and oligopeptides
trypsin (from pancreatic acinar cells) and other proteases further cleave peptides
triglycerides are broken down by lipases into 1 monoglyceride and 2 fatty acids
cholesterol esters are broken down by cholesterol ester hydrolase into 1 cholesterol and 1 fatty acid
phospholipids are broken down by phospholipase A2 into 1 lysolecithin and 1 fatty acid
lipid breakdown products enter the lacteal of a villi
protein breakdown products enter the capillary of a villi
monosaccharids enter the capillary of a villi