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Neurofibromatosis (ancillary (plain xray, brain CT/MRI, slit lamp…

- - - - visual loss
      - skin lesions
    - - cafe-au-lait spots
      - axillary/inguinal freckles
      - subcutaneous or cutaneous neurofibromas
      - asymmetric noncorrectable visual loss
      - lisch nodules
      - scoliosis
  - - - hearing loss
      - tinnitus
      - balance problems
    - - cranial nerve palsies
      - cafe-au-lait spots rare
      - subcutaneous neurofibromas
- - - - six or more cafe-au-lait
      - axillary or inguinal freckles
      - 2 or more typical neurofibromas or one plexiform neurofibroma
      - optic nerve glioma
      - two or more iris hamartomas
      - sphenoid dysplasia
      - first-degree relative
  - - - bilateral vestibular schwannomas
      - first degree relative
        
        AND
        
        unilateral vestibular schwannoma
        
        any two of
        
        meningioma
        
        schwannoma
        
        glioma
        
        neurofibroma
        
        posterior subcapsular lenticular opacities
      - unilateral vesitublar schwannoma
        
        AND any two of
        
        meningioma
        
        schwannoma
        
        glioma
        
        neurofibroma
        
        posterior subcapsular lenticular opacities
      - multiple meningiomas
        
        AND
        
        unilateral schwannoma
        
        any two of
        
        schwannoma
        
        glioma
        
        neurofibroma
        
        cataract
- - - - radiation
      - chemotherapy
    - - tumour resection
  - - - chemotherapy
      - laser
    - - resection of neurofibromas