Cardiovascular System

Heart

Fibrous Pericardium- Tough outer layer- Dense Connective Tissue- keeps heart from overfilling with blood, holds heart in place. Serous Pericardium- Double layered closed sac between heart and fibrous pericardium.

Pericardial Membranes

Epicardium- Filled with fat, visceral layer of serous pericardium. Myocardium- cardiac muscle tissue, contracts. Endocardium- lines heart chambers and covers heart valves.

Layers of Heart wall

Consist of cardiac muscle tissue that is of course striated and contracts. The branching networks of cardiac muscle cells are cardiac myofibers. The junctions are the intercalated disks. There are gap junctions that allow ions to pass between cells. In the intercellular space around each cardiac myofiber is the endomysium.

Brief Microscopic Anatomy of Myocardium

The right atrioventricular valve with 3 cusps. The left atrioventricular valve with 2 cusps. They open to allow blood flow and close to prevent a back flow of blood.

Heart Valves

Initiate each contraction sequence thus setting your heart rate. Specialized cardiac muscle cells that carry impulses through heart muscle signaling the chambers of the heart to contract in sequence.

Conduction System

Blood Vessels

Elastic Arteries- Largest- large lumen- more elastin than any other vessel. The thickness of these elastin results in weaker surges of blood pressure causing rhythmic contractions. Muscular Arteries- supply organs- "middle-sized"- thicker tunica media. Contains wavy internal elastic membrane in Tunica Intima and external elastic membrane in Tunica Media. Arterioles- smallest- Tunica Media contain 1 or 2 layers of smooth muscle cells

Artery Types

Continuous Capillaries- most common- occur in skeletal muscle, skin, and CNS. Tight junctions and desmosomes hold endothelial cells together. Intercellular clefts are present allowing small molecules to pass through. Fenestrated Capillaries- contain pores that stretch the endothelial cells. Only occur where there are high rates of small molecules being exchanged between blood and tissue fluid. Sinusoid Capillaries- wide, leaky. Follows twisted path with both wide and narrowed regions. Occur where there is exchange in large molecules like proteins or cells. Capillary beds- network of bodies smallest vessels.

Capillary Types

Venules-smallest veins-consist of endothelium. The lumen of a vein is larger than that of an artery. In a vein the Tunica externa is thicker than the Tunica media. Have less Elastin in their walls than arteries.

Veins

Blood

Blood Plasma is a straw-colored sticky fluid. It is 90% water but contains over 100 different kinds of molecules including nutrients, sugars, proteins, wastes, and oxygen. The three main types of proteins are Albumin, Globulin, and Fibrinogen.

Blood Plasma

Blood Cells or formed elements of blood are not erythrocytes or platelets. They cannot divide and are instead replaced in the bone marrow. Erythrocytes are red blood cells- small oxygen transporting cells. Leukocytes are white blood cells- far less abundant than erythrocytes but critical to bodies defense against disease.

Cells