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Ovary (Cell Types (Oocyte (big pink cell), Follicular Cells surround…

- - - - Ovum
        (just before fertilization
      - Primary Oocyte
        
        Immature gamete
        
        pink cytoplasm & nucleus
        
        Follicle =
        
        Primary Oocyte
        
        Rim of Follicular Cells
        
        FOLLICULAR PHASES (FSH):
        Stages Distinguished by:
        
        Size of 1* oocyte (small to large)
        
        Shape follicular cells (squamous to cuboidal)
        
        Layers of follicular cells (single to many)
        
        Fluid filled spaces inside follicle (none to large)
        
        Primordial Follicle
        
        3rd month to birth
        
        squamous Follicular cells
        single layer
        
        Primary Oocyte
        
        Primary Oocyte & GC Communication:
        
        Paracrine OR
        
        Gap junctions
        
        Primary Follicle
        
        Cuboidal Granulosa cells
        one-to-many layers
        
        Convert precursor to estrogen
        
        Primary Oocyte & GC Communication via ZP:
        
        Paracrine OR
        
        Gap junctions
        
        Granulosa Cells
        Secrete fluid rich in Estrogen & GAGs
        liquor folliculi
        
        1 more item...
        
        Stromal cells :arrow_right: Theca Interna Cells
        
        LH stimulates TI cells to make estrogen precursor
        
        Theca Interna
        White bubbles of lipid
        Steroid secreting
        
        1 more item...
        
        Theca Externa
        
        Fibroblasts
        
        SM
        
        Zona Pellucida
        surrounds Primary Oocyte
        
        Glycoprotein ECM
        
        Protects Oocyte
        
        Minimizes polyspermy (fertilization)
        
        NO blood follicle barrier (unlike testes)
        
        Secondary (antral) follicle
        
        Puberty = :arrow_up: FSH & Estrogen
        
        Follicule & Primary Oocyte grow rapidly
        
        Theca Interna
        White bubbles of lipid
        Steroid secreting
        
        Granulosa Cells
        Secrete fluid rich in Estrogen & GAGs
        liquor folliculi
        
        Space collecting liquor folliculi = Antrum
        
        indicates Secondary Follicle
        
        1 more item...
        
        Mature (Graafian) follicule
        
        "pre-ovulatory"
        
        Corona Radiata
        
        Granulosa Cells surround
        
        1 more item...
        
        Oocyte during ovulation
        
        Separate Antrums merge :arrow_right: C-shaped Antrum
        
        Atretic Follicle
        
        Most follicles do not reach ovulation
        
        Can happen any pre-ovulatory stage
        
        Degeneration 1* Oocyte + ZP (messy)
        
        Macrophages phagocytosed
        
        Post-Ovulation
        LUTEAL PHASE (LH)
        
        Blood fills antrum
        
        Follicle highly vascularized
        
        Peritoneum heals at ovulation site
        
        Corpus Leuteum =
        Granulosa Lutein Cells (Big & pale)
        :heavy_plus_sign:
        Theca Lutein Cells (small & dark)
        
        secretes progesterone
        
        Corpus Albicans
        
        scar-like degradation of CL
      - Secondary Oocyte
        
        Meiosis II
        
        LH SURGE
        
        Mature Follicle bulges
        
        Ovulation occurs at the Stigma
        
        Peritoneal Cavity
        
        Fimbriae of Uterine Tube