Cartilage CONNECTIVE TISSUE MESODERM

CELLS

FUNCTIONS & PROPERTIES

firm but flexible support

shock absorber

avascular

cells sit in lacunae

primary fiber: collagen type II

retain water

LOCATION

external ear, nose, lower respiratory tract, articular surfaces

GROWTH

APPOSITIONAL

differentiation from PERICHONDRIUM,

secrete matrix

CHONDROCYTE

INTERSTITIAL

cell division, existing cells

isogeneous group

4-8 cells of related cells

lengthening of bones

⭐ babies mostly made of cartilage skeleton

TYPES

Hyaline

most common

@ joints, nose, larynx, trachae, bronchi, ⭐ embryonic skeleton

macromolecules

PROTEOGLYCANS/GAGs

Glycoprotein

hyaluronic acid

keratin sulfate

chondroitin sulfate

Type II collagen

Blue in H&E

Elastic

@ external ear, epiglottis

special stain needed

where rebound is needed

elastic fibers

Fibrocartilage

where support and tensile strength are needed

@ capsules of joints, pubic symphysis, intervertebral discs

Types I & II collagen

structure btw cart. and dense regular connective tissue

pink w/fibers

lacunae

Chondrocytes

Chondroblasts

chondronectin