Cartilage CONNECTIVE TISSUE MESODERM
CELLS
FUNCTIONS & PROPERTIES
firm but flexible support
shock absorber
avascular
cells sit in lacunae
primary fiber: collagen type II
retain water
LOCATION
external ear, nose, lower respiratory tract, articular surfaces
GROWTH
APPOSITIONAL
differentiation from PERICHONDRIUM,
secrete matrix
➡ CHONDROCYTE
INTERSTITIAL
cell division, existing cells
➡ isogeneous group
4-8 cells of related cells
lengthening of bones
⭐ babies mostly made of cartilage skeleton
TYPES
Hyaline
most common
@ joints, nose, larynx, trachae, bronchi, ⭐ embryonic skeleton
macromolecules
PROTEOGLYCANS/GAGs
Glycoprotein
hyaluronic acid
keratin sulfate
chondroitin sulfate
Type II collagen
Blue in H&E
Elastic
@ external ear, epiglottis
special stain needed
where rebound is needed
elastic fibers
Fibrocartilage
where support and tensile strength are needed
@ capsules of joints, pubic symphysis, intervertebral discs
Types I & II collagen
structure btw cart. and dense regular connective tissue
pink w/fibers
lacunae
Chondrocytes
Chondroblasts
chondronectin