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Food Allergy Overview (Common food triggers (Fish/shellfish, Others - beef…

- - - - Introduce solids between 4-6months, starting with Fe rich foods and continuation of BFing
      - All infants should be given allergenic foods within 1st yr of life - inc high risk infants
      - Hydrolysed formula are not recommended for prevention of allergy
  - - - 'Lack hypothesis
        
        Explains close link between eczema and development of food allergy
        
        Sensitisation to allergen occurs through the skin and consumption of food induces oral tolerance
        
        Provides intervention strategies to prevent food allergy
        
        Research now targeting the skin barrier from early life using emollients to stop allergy developing
        
        LEAP and EAT studies followed
        
        Learning About Early Peanut allergies
        
        Study demonstrated peanut consumption within 1st yr of life prevents peanut allergy in high risk populations
        
        Effective in all races
        
        Emphasises need for continued consumption
        
        Enquiring About Tolerance
  - - - Caesarean delivery
      - General cleanliness
      - Antibiotics
    - - Conditions that support their proliferation
        
        Breastfeeding
        
        Longer gestation
        
        Vaginal delivery
      - Rich microbiota enables establishing immune system to develop a non-allergic state.
- - - - Allergens bind to IgE antibodies bound to mast cells
        
        Mast cell releases histamine and other inflammatory mediators
        
        Symtoms occur rapidly - mins to an hr