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Breathing Rate & Depth (determinant factors (PCO2 (major stimulus for…

- - - - (1) increased arterial PCO2 leads to increased CSF PCO2
      - (2) chemo-receptors in the brain stem sense increased PCO2
      - (3) respiratory rate increases
      - (4) this leads to increased elimination of CO2 at the alveoli = decresed arterial PCO2 (return to homeostasis)
    - - low arterial PCO2 causes cerebral vasoconstriction = reduces brain perfusion and produces cerebral ischemia