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Gas (Gas transport (O2 (Hemoglobin (Partial Pressures (Alveolar=100,…
Gas
Gas transport
O2
Hemoglobin
Structure
Adult Hb
Fetal Hb
Partial Pressures
Alveolar=100
Systemic capillary= 95
Atmospheric= 159
Tissue= 40
Affinity factors
Temperature
Blood pH
PO2
2,3 DPG
Plasma
Complications
Hypoxia
Anemic
Ischemic
Hypoxemic
Histotoxic
CO poisoning
Decreased P50 of CO= Increase affinity of o2 to heme
CO has higher affinity for heme
CO2
Gas exchange
Structure
Function
Gas laws
Henry
Fick
Dalton
Each gas contributes to its total
Gas regulation