Haemolytic: hereditary spherocytosis, glucose-6-phosphate dehydrogenase (G6PD) deficiency (defect in RBCs, X-linked, when pts exposed to oxidative stress), thrombotic thrombocytopenic purpura (TTP, thrombocytopenia & microangiopathic hemolytic anemia, renal insufficiency, schistocytes on smear), hemolytic uremic syndrome (thrombocytopenia, microangiopathic hemolytic anemia, renal insufficiency), AI hemolytic anemia (warm IgG binds RBC, +ve Coomb’s test, caused drugs, tx corticosteroids or splenectomy, cold agglutinin disease IgM binds RBCs), infections (malaria, babesiosis, sepsis), trauma, snake, insect bites