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Assembling Human Body (Tissues (Epithelia (Function (barrier, absorb,…

- - - - simple or stratified
      - squamous, cuboidal, or columnar
    - - barrier
      - absorb
      - secrete
    - - cover surfaces
      - line cavities
      - form glands
  - - - attached to bone
      - in some organs
    - - striated
        
        skeletal
        
        cardiac
      - smooth
    - - movement
  - - - communication
      - sensation
    - - neurons
      - glia
- - - - dehydration poorly depicts elasticicty
      - lose some components (lipids)
      - shrinkage
  - - - whole mounts & smears
      - light microscopy
        
        1-10 micrometers
        
        infiltrated with paraffin
      - electron microscopy
        
        50-150 nanometers
        
        infiltrated with plastic
    - - 3D organization from 2D images
      - must look at lots of sections
      - burger analogy
  - - - basophilic
      - blue/purple color
      - nucleic acids
    - - acidophilic
      - pink color
      - cytoplasm, mitochondria, extracellular
- - - - nuclear envelope
        
        lipid bilayer
        
        nuclear pore complex: mRNA out of nucleus
        
        attachment to ER
        
        nucleolus
        
        produces ribosomes
        
        not membrane bound
        
        makes ribosome subunit
    - - make ATP via cellular resp
    - - Smooth ER
        
        modify lipid structure
        
        transport lipids
      - Rough ER
        
        ribosomes synthesize proteins
        
        transport proteins
    - - cis/trans spaces
      - modify, embed into membrane, then ship
      - membrane turnover
    - - vessicles
        
        sequester things and move them (out)
      - lysosomes
        
        sequester things and clean up cell
      - peroxisomes
  - - - Microfilaments
        
        actin (microvilli)
      - Intermediate Filaments
        
        true skeleton of cell
        
        shape/integrity
        
        link cells together
        
        link to extracellular fibers
        
        critical for movement
        
        material within cell
        
        along cell surface
        
        moving actual cell
      - Microtubules
        
        centrioles
        
        flagella
        
        cilia
      - Ribosomes
      - Proteasomes
        
        inside lysosome to help breakdown
- - - - difference btwn extracellular and intracellular components
  - - - ampipathic
      - crossing: Non-polar
      - not crossing: polar, ionic
    - - channels
      - transporters
      - receptors
      - enzymes
      - linkers/anchors
      - cell identity markers
      - can change in minutes!
    - - ammt of cholesterol
      - alignment of fatty acid tails
    - - Passive
        
        diffusion
        
        osmosis
        
        facilitated diffusion
        
        filtration
      - Active
        
        endocytosis
        
        in
        
        exocytosis
        
        out
        
        phagocytosis
        
        big
        
        pinocytosis
        
        water
        
        receptor mediated