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CARDIOMYOPATHIES (Dilative CM (Secondary forms of cardiomyopathy…

- - - - class II a
        CHF: NYHA II, III, IV. optimal pharmacotherapy
        ECG: QRS >150 ms, NON-LBBB, sinus rhythm
        Echo: LVEF ≤ 35%
      - class I
        CHF: NYHA II, III, IV. optimal pharmacotherapy
        ECG: QRS >120 ms, LBBB, sinus rhythm
        Echo: LVEF ≤ 35%
  - - - Risc factors: mother’s age, black race, multipara, twin pregnancy
        Mother mortality 30-60% - Infant martality 20%
        Omnious risc factors: cardiomegaly and low LVEF > 6 months after birth
        50% of patients – recovery of LVEF within 6 months
    - - Genetic predisposition, Malnutrition
        Clinical signs: heart failure, arrhythmia, chest pain
        Echo: diastolic dysfunction --> decrease LVEF --> LV enlargement
        Reversible in case of early and TOTAL abstinence
    - - SVT, AF, sinus tachycardia
        mechanism: calcium overload of cardiomyocyte
        Reversible in case of normal rhythm restoration
- - - - gradient in rest
        
        Symptoms: dyspnoe (90% of patients), chest pain (80%), syncope (30%), presyncope, dizzy spells, palpitations
        
        Complications:
        • AF --> embolic events
        • VT / VF --> sudden cardiac death
        • DECREASE systolic function / LV dilatation --> CHF (10%)
  - - - ECG: left ventricular hypertrophy, ST and T wave changes, and abnormal Q waves especially in the inferolateral leads.
        
        Echocardiography :asymmetric left ventricular hypertrophy
        
        Cardiac MR, Genetic analysis