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Hallucinogens (Pharmacology (Binding to 5-HT receptors (hallucinations…
Hallucinogens
Pharmacology
hallucinogens vary widely in potency, ranging from LSD as the most potent to mescaline as the least
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effects of smoked DMT and Salvia felt within seconds, peak over a few minutes, and are gone within an hour
Most hallucinogenic drugs have either a serotonin-like (indoleamine) or catecholamine-like structure
Serotonin like/ indoleamine = LSD, psilocybin, DMT, etc
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catecholamine-like (phenethylamine) = mescaline, TMA, and DOM
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Salvinorin A
Salvia divinorum - member of the mint family native to Mexico and is historically used in religious rituals by shamans
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LSD
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synthesized in 1938 from ergot, a parasitic fungus on rye
ergot is very toxic, produces powerful contractions of the uterus that can help trigger labor and reduce post-birth uterine hemorrhage
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Mescaline
found in several species of cactus, such as peyote
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Psilocybin
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Timothy Leary and Richard Alpert at Harvard experimented with psilocybin and LSD and helped to popularized these drugs
General
Effects
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can produce flashbacks
if persistent, the individual is considered to be suffering from hallucinogen persisting perception disorder (HPPD
with a few exceptions, prolonged psychotic episodes typically involve individuals who had already been diagnosed with a psychotic disorder or who had pre-psychotic symptoms before taking the drug
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