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Immunity (1st and 2nd Lines: Innate Defenses (non-specific, always…

- - - - interferons
        (stimulate production of antiviral proteins)
      - complement proteins
        (create pores in membrane of pathogens; cause lysis)
    - - Nautral Killer cells
        (create pores in membrane of infected/abnormal cells; cause lysis)
      - Phagocytes
        (engulf and digest pathogens
        display foreign antigens bound to MHC on surface)
  - - - Mast cells release chemical signals (e.g. histamine) in response to tissue injury
      - Phagocytes and platelets migrate to site of tissue injury to fight pathogens and aid in clotting
- - - - Clump pathogens together so they can be engulfed by phagocytes more easily
      - Recruit complement proteins to destroy pathogens by lysis
      - Surround pathogens to prevent them from infecting cells