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CACNG2 tail and AMPAR kinetics (GluA2(Q)-CACNG4 and GluA2(Q)-CACNG4/2…
CACNG2 tail and AMPAR kinetics
GluA2(Q)-CACNG4 and
GluA2(Q)-CACNG4/2 tandems
No
Switch to stg CGC and SC (to show absence of AMPAR subunit specificity) - NASPM
Yes
#
Increase CACNG4 stretch length until properties match those of CACNG4
Paste the region in CACNG4 (check also for specific residues in alignment)
Yes
Check if this domains transfer to other TARPs
No
Mutate CACNG2 segment
No
Yes
Check for phosphorylation sites
#
Try CACNG2/4
Yes
No
Is deact/desens time increased by CACNG2 Ct?
Is decay time faster than CACNG2?
Is decay time faster than CACNG2?
Is decay time slower than CACNG4?