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Heaptocarcinoma & transplant (s/s (pain @ RUQ, Palpable mass, enlarged…
Heaptocarcinoma & transplant
HCC
cause
male > female
related to HBV & HCV
Cirrhosis
s/s
pain @ RUQ
Palpable mass
enlarged liver
weight loss
cirrhosis / hepatitis
juandice
LFT impairment
hyperbilirubinemia
Rx
resection
transplant
RFA
raduifrequency Ablation
Neoadjuvant/Palliative
trans-arterial chemioembolization TACE
inject chemo intra-arterially to segemetnal heaptic artery that supply to tumor
Doxorubicin
cisplatin
liopodol
chemotherapy
radiotherapy
supportive therapy
Coplementary therapy
targeted agents
Bevacizumab
antibody to angigenic factor vascular endothelial growth factor
use of
interferon alpha
transplant
indication
treatment of choice early stage HCC
end stage liver disease