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Disorders with Dementia (Wilson's Disease (Sx (Neurologic dementia…
Disorders with Dementia
Wilson's Disease
Et.
order of copper metabolism
Sx
Neurologic dementia
progressive
increased muscular rigidity
tremor
Dysarthria
Note:
progressive
corneal pigmentation
onset 10-25
Huntington's
Et.
Basal ganglia
Lack of GABA (excitatory) = too much inhibition
Sx
Dementia
Chorea (jerking mvmt
Intentional tremor (during voluntary mvmts)
Note:
Hereditary
onset in post-puberty
3rd decade of life
Think of "13" in House who only had 3 more years to practice surgery before she would show Sx
MVMT disorder
Hydrocephalus
Et
inability to absorb or drain fluid
shunt
swelling of ventricles
difficulties gait (mobility)
incontinance
gradual slowing mental processing
dementia
atrophy of preventricular region
neurolgic
Creutzfeldt-Jakob Disease
Mad cow
Et
Infections protiens in brain
diagnose with MRI
Sx.
mood changes
seizures
terminal
Lewy Body Disease
Lewy bodies (protein deposits) in substantia nigra and cortex
variant of Parkinsons (substantia nigra and dopamine)
Dementia
motor deficits
Alsheimer's Disease
Beta-amaloyid plaques and tangles in brain
Sx
dementia
disorientation
impaired judgement
language and cognitive problems
anterograde amnesia (cant form new memories