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Protein related disorders (Lewy Body Dementia (Sx (Dementia (neurologic),…
Protein related disorders
Pick Disease
Et.
Frontal temporal lobe
abnormal protein (Pick bodies) production in brain
Sx
Degenerative dementia
progressive aphasia (nonfluent)
Broca's (B.A.44/45)
Lewy Body Dementia
Et.
protein deposits (Lewy Bodies) in substatia nigra and cortex
Sx
Dementia (neurologic)
Motor deficits
*Variant of Parkinson's (note involvement of substantia nigra)
Creutzfeld-Jakob Disease
Et.
infections protein in brian
Note: mad cow is strain of CJ disease
Sx
Dementia (systemic)
Mood changes
seizures
terminal illness (6-12 mo)
*Note: diagnose with MRI