Peptic Ulcer - ulceration in the mucosa of the lower oesophagus, stomach, duodenum

cause

mucosal cytoprotection is deficient

excessive acid secretion & autodigestion occurs

multifactorial: inflammation, acid secretion abnormality, mucosal barrier efffect

clinical manifestation

epigastric pain

weight loss

haemorrhage

perforation

tenderness

Indication: sudden, intense midepigastricnpain radiating to the right shoulders

hematemesis/ melaena

anaemia, dizziness, syncope

occurs in duodenal ulcer

s/s if acute symptoms of acute abdomen with sudden onset of severe, localised epigastric pain

peritonitis develops when pain become generalised right abdomen with decrease bowel sounds and shock

diagnostic studies

Lab test

imaging studies

test for H. pylori

C-urea breath test

serum ELISA

pyloritek

abdominal X-ray

barium study

oseophagogastroduodenoscopy (OCD)

fluoroscopic & x-ray examination : barium swallow

indication

nursing care

low residue diet 2-3 days prior to the test

NPO for 8 hrs

withhold medication for 8 Hours unless otherwise indicated

bring V-ray films

nursing assessment

pain assessment

visceral pain - caused by stretching/inflammation of a hollow muscular organ

somatic pain - arises from the parietal peritoneum

focused history

diet & nutrition

medication

aspirin

NSAIDs

steroids

bowl history

psychosocial exam & abdominal assessment

vital signs

premorbid status

medication

antacids

H2RA

PPI

pepsin inhibitor

magnesium hydroxide - triact

famotidine - pepcidine

pantoprazole (pantoloc)

sucralfate - carafate

side effect: GI disturbances -
constipation, diarrhoea, rebound hyperacidity

indication : short term relief of heartburn

therapeutic actions: neutralize gastric acids, increase stomach PH

therapeutic actions: inhibits stimulation of gastric parietal cells at H2 receptor sites, decrease gastric acid secretion, promote healing of acid-sensitive ulcer

indication: S/S unresponsive to antacid

side effect:

  • CNS: confusion;
  • GI: nausea, diarrhea, abdominal pain

therapeutic actions: reduce gastric secretion

indication: severe erosive GERD, not responsive to H2RA

side effect: overproduction of gastrin
CNS: headache, dizziness, fatigue
GI: nausea, diarrhea, abdominal pain

antiemetics - treat underlying cause of nausea, vomiting

prochlorperazine (stemetil)

nursing intervention

avoid fluid volume deficit

achieving pain relief

achieving adequate nutrition

client education on treatment regimen

surgery

indication

haemorrhage

obstruction

oerforation

acid reduction

severe ulcers / difficulty with medical regimen compliance

vagotomy

pyloroplasty & vagotomy

antrectomy & vagotomy

subtotal gastrectomy

gastroduodenostomy

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